Gamma Dodecalactone Scentspiracy bedoukian fragrance ingredient molecule shop
Gamma Dodecalactone Scentspiracy bedoukian fragrance ingredient vial shop
Gamma Dodecalactone Scentspiracy bedoukian fragrance ingredient molecule shop
Gamma Dodecalactone Scentspiracy bedoukian fragrance ingredient vial shop

Gamma Dodecalactone FCC N° 455

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Gamma Dodecalactone FCC N° 455 is characterized by its luxurious waxy and fatty essence, complemented by a delectably sweet fragrance. It features subtle undertones reminiscent of a fresh green rind, enriching its complex aroma.

This compound masterfully contributes a warm, creamy note, enhancing the depth and richness of fragrances, making them more inviting and nuanced.

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Premium Synthetic Ingredient for Perfumery

Gamma Dodecalactone FCC N° 455 is characterized by its luxurious waxy and fatty essence, complemented by a delectably sweet fragrance. It features subtle undertones reminiscent of a fresh green rind, enriching its complex aroma.

This compound masterfully contributes a warm, creamy note, enhancing the depth and richness of fragrances, making them more inviting and nuanced.

Technical Ingredient Overview

  • 🏭 Manufacturer — Bedoukian Research Inc.

  • 🔎 Chemical Name — 5-Octyloxolan-2-one

  • 🧪 Synonyms — γ-Dodecalactone; γ-Dodecanolactone; γ-Laurolactone; 4-Dodecanolide; 5-Octyldihydro-2(3H)-furanone; Dodecanoic acid 4-hydroxy-, γ-lactone

  • 🧬 Chemical Formula — C₁₂H₂₂O₂

  • 📂 CAS — 2305-05-7

  • 📘 FEMA — 2400 (FEMA, 1998)

  • ⚖️ Molecular Weight — 198.30 g mol⁻¹

  • 📝 Odor Type — Fruity peach-cream

  • 📈 Odor Strength — Medium diffusion

  • 👃🏼 Odor Profile — Sweet peach–apricot, creamy, waxy-fatty, soft green rind nuance

  • ⚗️ Uses — Peach & tropical accords, creamy florals, gourmand “milk/skin” effects, flavour enhancer for stone-fruit and dairy profiles

  • 🧴 Appearance — Colourless to pale-yellow oily liquid

What is Gamma-Dodecalactone?

Gamma-Dodecalactone (γ-dodecalactone) is a 12-carbon γ-lactone with a five-membered cyclic ester and an n-octyl side chain. This ring size shifts its odour from the coconut-like freshness of δ-lactones toward a richer, waxy-creamy peach character (Arctander, 1969).

Naturally, it occurs at trace levels in:

  • ripe stone fruits such as peach and nectarine (Pino et al., 2005),

  • tropical fruits like mango (Mangifera indica) and guava (Good Scents Company, n.d.),

  • strawberries, butter, and milk (Keeney & Patton, 1956).

Commercial production relies on hydrogenation of ricinoleic acid (castor oil), oxidation, and lactonisation (ChemicalBook, n.d.). Modern white-biotech methods using Yarrowia lipolytica achieve high-efficiency biosynthesis (IFF Patent EP0578388, 1994).

With its C-12 chain, γ-dodecalactone bridges juicy top notes and persistent musky bases in perfumery (Arctander, 1969).

Historical Background

  • 1930s–1950s – Medium-chain γ-lactones linked to the “coconut” off-flavour of dairy fat (Keeney & Patton, 1956).

  • 1958 – Lever Brothers patented γ-lactones for margarine flavouring (US Patent 2819169 A).

  • 1969 – Arctander highlighted its “extraordinary tenacity” in heavy florals

  • 1980s – First microbial bioconversion to natural γ-lactones (US Patent 4560656 A).

  • 1994 – IFF scaled Yarrowia fermentation (EP0578388).

  • 1998 – FEMA GRAS reaffirmed; JECFA issued full specification (JECFA, 1998).

  • 2020s – IFRA Transparency List confirms no restrictions (IFRA, 2022).

Olfactory Profile & Perfumery Applications

Descriptors: Peach flesh, apricot nectar, creamy-fatty wax, soft green (Arctander, 1969).

Volatility: Base-to-heart; boiling point ≈ 257 °C (JECFA, 1998).

Typical uses:

  • Peach, apricot & tropical accords (0.05–0.5 %) to heighten realism.

  • Creamy florals (0.01–0.2 %) for lactonic body.

  • Gourmand/dairy accords (0.1–1 %) for warm-milk nuances with heliotropin or vanillin.

  • Aldehydic powders & musks (trace–0.1 %) to soften sharp aldehydes.

Explore related ingredients: γ-Decalactone, δ-Dodecalactone, Ionone Alpha, Heliotropin, Coumarin.

Industrial & Technical Uses

  • Flavour additive in dairy, beverages and fruit preparations (FEMA 2400; JECFA, 1998).

  • Cosmetic fragrance component imparting soft “clean-skin” nuances.

  • Research substrate for lactone biosynthesis studies.

Regulatory & Safety Overview

  • IFRA 51st Amendment: Not restricted (IFRA, 2022).

  • EU Cosmetics Regulation 1223/2009: No allergen labelling required.

  • FEMA Status: FEMA 2400 (JECFA, 1998).

  • GHS Classification: Skin Irrit. 2; Eye Irrit. 2A; STOT SE 3 (ChemicalBook, n.d.).

  • REACH: Registered, EC 218-971-6 (1–10 t/y).

  • Transport: Not regulated as hazardous (IMDG/IATA/DOT).

References

  • Arctander, S. (1969). Perfume and Flavor Chemicals (Vols. I–II). Author.

  • ChemicalBook. (n.d.). 4-Dodecanolide (CAS 2305-05-7) — Chemical properties.

  • Cheméo. (n.d.). γ-Dodecalactone — Chemical data.

  • FEMA. (1998). Flavor Ingredient Library — 2400.

  • Good Scents Company. (n.d.). γ-Dodecalactone profile.

  • IFRA. (2022). Transparency List — γ-Dodecalactone.

  • International Flavors & Fragrances. (1994). Patent EP0578388.

  • JECFA. (1998). Evaluation of Flavouring Substances — γ-Dodecalactone.

  • Keeney, P. G., & Patton, S. (1956). The coconut-like flavour defect of milk fat. Journal of Dairy Science, 39, 1104–1113.

  • Pino, J. A., Mesa, J., Muñoz, Y., Martí, M. P., & Marbot, R. (2005). Volatile components from mango (Mangifera indica L.) cultivars. Journal of Agricultural and Food Chemistry, 53(6), 2213–2223.

  • United States Patent US 2819169 A (1958). Process of Flavouring Margarine.

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