Ambrinol S (CAS 41199-19-3, 31499-72-6) – Technical Ingredient Overview
🏭 Manufacturer — Symrise
🔎 Chemical Name — The product data sheet lists 1,2,3,4,4a,5,6,7-octahydro-2,5,5-trimethyl-2-naphthol and 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)butan-2-one.
📂 CAS Number — 41199-19-3 and 31499-72-6, as listed for Ambrinol S 690993.
📝 Odor Type — Animalic and ambergris.
🧴 Appearance — Clear, colorless liquid.
💧 Density — Specific gravity d20/4: specification 0.9370–0.9510; batch 66421 result: 0.9403.
🔍 Refractive Index — nD at 20 °C: specification 1.4850–1.4930; batch 66421 result: 1.4885.
🔥 Flash Point — Above 100 °C (Symrise, n.d.).
What is Ambrinol S?
Ambrinol S 690993 is a synthetic perfumery material by Symrise (BLH, n.d.). Its product sheet lists two chemical names and two CAS numbers.
Historical Background
The story of ambrinol begins with the study of natural ambergris. One of its main constituents, ambrein, has only a mild scent; its oxidation can produce odorants including ambrinol and ambroxide (American Chemical Society, 2020). (−)-cis-α-Ambrinol is among the compounds found in natural ambergris (López-Martínez et al., 2023).
According to dsm-firmenich, its research into ambergris began in the 1930s and led to the synthesis of Ambrox and Ambrinol in the 1950s (dsm-firmenich, n.d.). Firmenich's historical account lists Grisambrol, a specialty containing both materials, in 1954 (Firmenich, 2016).
In her review, Anonis (1995) reports that Mookherjee and Patel identified α-ambrinol among the volatile constituents of an ambergris tincture in their 1977 work.
Research into α-ambrinol synthesis continues. López-Martínez et al. (2023) described a route starting from α-ionone; their work concerns the molecule, not a disclosed manufacturing route for Ambrinol S.
Olfactory Profile
The following profile is based on Symrise (n.d.).
Main Descriptors: Musk, earthy and violet facets accompany the animalic ambergris character.
Intensity: Symrise reports an air threshold of 0.0063 µg/L.
Tenacity: Approximately one day on a blotter, as read from the manufacturer's chart.
Applications in Fine Fragrance
Symrise (n.d.) describes these uses:
Musky compositions — An increase in volume and performance in the musky part of a fragrance.
Amber accords — The material can add a natural aspect to amber ingredients.
Leather accords — It can bring out an animalic-floral facet.
Performance in Formula
Symrise (n.d.) recommends use from traces up to 1% in perfumery.
Stability: The manufacturer presents odor and discoloration results after three months at 40 °C in several product bases; results vary by base.
Industrial & Technical Uses
Symrise (n.d.) includes the following matrices in its stability assessment:
Functional Perfumery — Fabric softener, detergent and cleaner.
Personal Care — Soap, deodorant, shampoo, shower gel, hair conditioner and body lotion.
Sustainability Credentials
Symrise reports 39.0% biodegradability and describes the material as partly biodegradable (Symrise, n.d.).
Related Ingredients on Scentspiracy
Explore Ambrox® Super for an ambergris-inspired material, or Ambrettolide for a musky direction.
FAQs
Is Ambrinol S the same as a single α-ambrinol molecule?
Symrise lists two chemical names and two CAS numbers in the Ambrinol S 690993 product data sheet (Symrise, n.d.).
Where can Ambrinol S be used in perfumery?
Symrise describes uses in musky, amber and leather compositions (Symrise, n.d.).
References
American Chemical Society. (2020, March 9). Ambrein. https://www.acs.org/molecule-of-the-week/archive/a/ambrein.html
Anonis, D. P. (1995). Amber notes in perfumery: Ambergris. Perfumer & Flavorist, 20. https://img.perfumerflavorist.com/files/base/allured/all/document/2016/02/pf.9503.pdf
BLH. (2026). Certificate of analysis: Ambrinol S 690993, batch 66421 [Certificate of analysis]. Stock record.
BLH. (n.d.). Ambrinol S 690993. https://shop.blhsas.com/ambrinol-s-690993-c2x29840799
dsm-firmenich. (n.d.). Ambrinol. https://studio.dsm-firmenich.com/product/ambrinol-pe-908930-0
Firmenich. (2016). Ambrox® Super: History and legacy [Perfumery ingredients brochure]. https://www.firmenich.com/sites/default/files/2020-10/Sharing-innovation-perfumery-2016.pdf
López-Martínez, J. L., Torres-García, I., Moreno-Gutiérrez, I., Oña-Burgos, P., Rosales Martínez, A., Muñoz-Dorado, M., Álvarez-Corral, M., & Rodríguez-García, I. (2023). A concise diastereoselective total synthesis of α-ambrinol. Marine Drugs, 21(4), 230. https://doi.org/10.3390/md21040230
Symrise. (n.d.). Ambrinol S 690993 [Product data sheet]. https://www.symrise.com/fileadmin/symrise/Marketing/Scent_and_care/Aroma_molecules/Ingredient_finder/SYM_PC_Datenblaetter/SYM_PC-Ambrinol_S.pdf
Technical profile written by Scentspiracy. Sources are listed below. Last updated: November 2026.